Since 2010 both Melbourne and the Western Bulldogs have hosted a single 'home' game each year at the stadium, except for 2011 when Richmond hosted a game rather than the Western Bulldogs. Between 2004 and 2008 a single Western Bulldogs 'home' game was the only AFL season game played at the ground. Port Adelaide also had had a three-year deal with the Northern Territory government and Marrara Stadium, in which Port would play two 'away' games at TIO Stadium each year between 2009 and 2012.
TIO Stadium has hosted AC/DC for their "Ballbreaker" tour in November 1996, when 13,000 fans and 170 tonnes of equipment packed the ground. Sir Elton John performed for the first time in the Northern Territory, at TIO Stadium on the 17 May 2008 as part of the his Australian Tour.