Costanzo was born in Rome.
He began his career as a journalist, and in the late 1970s appeared in several television shows, before creating his most famous show, The Maurizio Costanzo Show, currently the most important and longest-lasting talk show in Italy. Costanzo's TV style includes subtle, low-profile irony.
He is also the "communication-agent" (an aesthetical and rhetorical consultant for public appearances) of many important Italian political leaders. Costanzo was a proven member of the Propaganda 2 masonic lodge (membership number 1819).
His son Saverio is a film director.
- 1968 - A qualsiasi prezzo, of Emilio P. Miraglia
- 1969 - I quattro del pater noster, of Ruggero Deodato
- 1969 - Il giovane normale,of Dino Risi
- 1970 - Cerca di capirmi, of Mariano Laurenti
- 1976 - Al piacere di rivederla,of Marco Leto
- 1976 - Bordella, of Pupi Avati
- 1976 - La casa dalle finestre che ridono, of Pupi Avati
- 1977 - L'altra metà del cielo,of Franco Rossi
- 1977 - Una giornata particolare,of Ettore Scola
- 1977 - Tutti defunti... tranne i morti,of Pupi Avati
- 1978 - Melodrammore,of Mauricio Costanzo
- 1978 - Jazz band - Film TV,of Pupi Avati
- 1979 - Cinema!!! - Film TV,of Pupi Avati
- 1983 - Zeder,of Pupi Avati
- 2003 - Per sempre,of Alessandro Di Robilant
- 2005 - Troppo belli, of Ugo Fabrizio Giordani
- 2007 - Voce del verbo amore, of Andrea Manni
- Maurizio Costanzo at the Internet Movie Database
- Maurizio Costanzo's program website