Mayhem Festival 2011 was the fourth annual Mayhem Festival created by Kevin Lyman. The official lineup was announced on January 31, 2011. It was the first year that the festival utilized a rotating main stage slot, and the first year that the tour had more than one act returning from previous lineups.
The 2011 iteration of Mayhem Festival was notable as the first year in which the tour utilized multiple acts to fill the opening slot on the Main Stage on different ranges of days. Machine Head opened the Main Stage from the tour's onset until July 20th, Trivium performed from July 22nd to August 2nd, and In Flames played from August 3rd until they dropped off the tour. While one band opened the main stage, the other two instead performed as headliners on the Jägermeister Mobile Stage and Revolver Stage.
On July 31st, Swedish band In Flames announced that they would not be able to continue touring with the festival by posting this on their official website: "It is with huge regret that today with immediate effect In Flames must cancel their current US shows as part of the Mayhem tour and their own US Headline shows. But due to a serious terminal illness of one the band’s immediate family members they feel they have no option. We have had the most amazing and fun times as part of the Mayhem tour and we are truly grateful for all the support the whole festival has shown. We will be back at the start of 2012. Once again our apologies"