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Meclonazepam structure.svg
Systematic (IUPAC) name
Clinical data
Legal status ?
CAS number 58662-84-3 N
ATC code None
PubChem CID 3033985
ChemSpider 2298544 YesY
Chemical data
Formula C16H12ClN3O3 
Mol. mass 329.74
 N (what is this?)  (verify)

Meclonazepam[1] ((S)-3-methylclonazepam) was discovered by a team at Hoffmann-La Roche in the 1970s and is a drug which is a benzodiazepine derivative similar in structure to clonazepam.[2] It has sedative and anxiolytic actions like those of other benzodiazepines,[3] and also has anti-parasitic effects against the parasitic worm Schistosoma mansoni.[4]

See also[edit]


  1. ^ U.S. Patent 4,031,078
  2. ^ The Lundbeck Institute. "Meclonazepam". Psychotropics. Lundbeck. 
  3. ^ Ansseau, M.; Doumont, A.; Thiry, D.; Von Frenckell, R.; Collard, J. (1985). "Initial study of methylclonazepam in generalized anxiety disorder. Evidence for greater power in the cross-over design". Psychopharmacology 87 (2): 130–135. doi:10.1007/bf00431795. PMID 3931136.  edit
  4. ^ O'Boyle, C.; Lambe, R.; Darragh, A. (1985). "Central Effects in Man of the Novel Schistosomicidal Benzodiazepine Meclonazepam". European Journal of Clinical Pharmacology 29 (1): 105–108. doi:10.1007/bf00547377. PMID 4054198.  edit

Further reading[edit]

  • Abdul-Ghani, R. A.; Loutfy, N.; Hassan, A. (2009). "Experimentally promising antischistosomal drugs: A review of some drug candidates not reaching the clinical use". Parasitology Research 105 (4): 899–906. doi:10.1007/s00436-009-1546-2. PMID 19588166.  edit