Mefenorex

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Mefenorex
Mefenorex.svg
Systematic (IUPAC) name
3-chloro-N-(1-methyl-2-phenylethyl)propan-1-amine
Clinical data
Legal status ?
Identifiers
CAS number 17243-57-1
ATC code A08AA09
PubChem CID 21777
ChemSpider 20467 YesY
UNII K98M4N387W YesY
KEGG D07891 YesY
Chemical data
Formula C12H18ClN 
Mol. mass 211.731
 YesY (what is this?)  (verify)

Mefenorex (Rondimen, Pondinil, Anexate) is a stimulant drug which was used as an appetite suppressant. It is an amphetamine derivative which was developed in the 1970s and used for the treatment of obesity.[1][2] Mefenorex produces amphetamine as a metabolite,[3] and has been withdrawn in many countries despite having only mild stimulant effects and relatively little abuse potential.[4]

References[edit]

  1. ^ Vincendeau MJ. A new regulator of appetite: mefenorex. (French). Bordeaux Medical. 1970 Jul-Aug;3(7):1951-3.
  2. ^ Beyer G, Huth K, Muller GM, Niemoller H, Raisp I, Vorberg G. The treatment of obesity with the appetite curbing agent Mefenorex. (German). Die Medizinische Welt. 1980 Feb;31(8):306-9.
  3. ^ Rendic S, Slavica M, Medic-Saric M. Urinary excretion and metabolism of orally administered mefenorex. European Journal of Drug Metabolism and Pharmacokinetics. 1994 Apr-Jun;19(2):107-17.
  4. ^ Engel J, Kristen G, Schaefer A, von Schlichtegroll A. Mefenorex (Rondimen). Drug and Alcohol Dependence. 1986 Jun;17(2-3):229-34.