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Meisner developed this technique after working with Lee Strasberg and Stella Adler at the Group Theatre and while working as head of the acting program at New York City's Neighborhood Playhouse. He continued its refinement for fifty years.
Meisner Training is an interdependent series of training exercises that build on one another. The more complex work supports a command of dramatic text. Students work on a series of progressively complex exercises to develop an ability to first improvise, then to access an emotional life, and finally to bring the spontaneity of improvisation and the richness of personal response to textual work. The techniques developed the behavioral strand of Stanislavski's. The technique is used to develop improvisation skills as well as "interpreting a script, and creating the specific physical characteristics of each character the actor played" and is still taught as an acting technique at the Sanford Meisner Center in Los Angeles. 
- Repetition- "In this exercise, two actors sit across from each other and respond to each other through a repeated phrase. The phrase is about each other's behavior, and reflects what is going on between them in the moment, such as "You look unhappy with me right now." The way this phrase is said as it is repeated changes in meaning, tone and intensity to correspond with the behavior that each actor produces towards the other. Through this device, the actor stops thinking of what to say and do, and responds more freely and spontaneously, both physically and vocally. The exercise also eliminates line readings, since the way the actor speaks becomes coordinated with his behavioral response."
List of Meisner-trained actors
Prominent actors who trained at The Neighborhood Playhouse or elsewhere in the Meisner technique include:
- Aaron Eckhart
- Aaron Lind
- Alec Baldwin
- Alexandra Daddario
- Amanda Setton 
- Amy Schumer 
- Billy Sharpe
- Christoph Waltz 
- Christopher Lloyd
- Christopher Meloni
- Connie Britton
- David Duchovny
- Diane Keaton
- Dylan McDermott
- Geraldine Page
- Grace Kelly
- Gregory Peck
- Hannah New 
- Illeana Douglas
- James Caan
- James Franco
- James Gandolfini 
- Jason Priestley 
- Jeff Bridges
- Jeff Goldblum
- Jennifer Sky
- Jessica Walter
- John Turturro
- Jon Voight
- Karl Urban 
- Krysten Ritter 
- Louise Lasser
- Leslie Nielsen
- Mark Rydell
- Mary Steenburgen
- Michael K. Williams
- Michelle Pfeiffer
- Naomi Watts
- Nick Ferrucci
- Noah Emmerich
- Paul Sorvino
- Raymond Mamrak
- R.J. Adams
- Renee O'Connor
- Robert Duvall
- Roger Bart
- Sandra Bullock[not in citation given]
- Scott Caan
- Sean Astin
- Sherie Rene Scott
- Stephen Colbert 
- Steve McQueen
- Sydney Pollack
- Tatiana Maslany 
- Tina Fey
- Tom Cruise
- Ty Burrell
- Wil Wheaton 
- Hirsch (2000, 498).
- "Between Takes at CBS - Amanda Setton". CBS. Retrieved 2013-10-29.
- "Amy Schumer Biography". TV Guide. Retrieved 2014-04-15.
- "Christoph Waltz - Dill Pickle". YouTube. Retrieved 2013-08-19.
- "IMDB bio". Retrieved 6 February 2014.
- Itzkoff, Dave (19 June 2013). "James Gandolfini Is Dead at 51; a Complex Mob Boss in ‘Sopranos’". The New York Times. p. 2. Retrieved 19 June 2013.
- http://corogues.com/the-curriculum/meisner-training. Missing or empty
- http://johnsonlaird.com/assets/documents/1569/1569_actor_biography.pdf. Missing or empty
- http://m.fastcocreate.com/1681796/krysten-ritter-on-how-to-be-a-likeable-bitch. Missing or empty
- "Stephen Colbert shmoozes about family deaths". YouTube. Retrieved 2013-08-19.
- "Conversations with Tatiana Maslany of ORPHAN BLACK". YouTube. Retrieved 2014-05-11.
- "A post about acting, and the imporance of keeping it simple". 2013-11-08.
- Banham, Martin, ed. 1998. The Cambridge Guide to Theatre. Cambridge: Cambridge UP. ISBN 0-521-43437-8.
- Courtney, C. C. 2000. "The Neighborhood Playhouse." In Krasner (2000b, 291-295).
- Hirsch, Foster. 2000. "Actors and Acting." In Wilmeth and Bigsby (2000, 490-513).
- Hodge, Alison, ed. 2000. Twentieth Century Actor Training. London and New York: Routledge. ISBN 0-415-19452-0.
- Krasner, David. 2000a. "Strasberg, Adler and Meisner: Method Acting." In Hodge (2000, 129-150).
- ---, ed. 2000b. Method Acting Reconsidered: Theory, Practice, Future. New York: St. Martin's P. ISBN 978-0-312-22309-0.
- Longwell, Dennis, and Sanford Meisner. 1987. Sanford Meisner on Acting. New York: Random House. ISBN 978-0-394-75059-0.
- Postlewait, Thomas. 1998. "Meisner, Sanford." In Banham (1998, 719).
- Silverberg, Larry. 1994. The Sanford Meisner Approach: An Actor’s Workbook. Workbook One. New Hampshire: Smith and Kraus. ISBN 978-1-880399-77-4.
- Wilmeth, Don B, and Christopher Bigsby, eds. 2000. The Cambridge History of American Theatre. Vol 3. Cambridge and New York: Cambridge UP. ISBN 978-0-521-66959-7.
- Sanford Meisner at the Internet Movie Database
- The Acting Studio-New York; Meisner protege
- The Neighborhood Playhouse School of the Theatre
- The Sanford Meisner Center
- Meisner Acting - The Maggie Flanigan Studio
- Meisner Technique at the Michelle Danner Studio
- The New York Studio for Stage & Screen in Asheville; Meisner training in the Southeast