Meissner's plexus

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Meissner's plexus
The plexus of the submucosa from the rabbit. X 50.
GI Organization.svg
Latin Plexus nervosus submucosus, plexus submucosus,
plexus Meissneri
Gray's p.1177
MeSH A08.800.050.050.850
TA A14.3.03.042
FMA 63252
Anatomical terms of neuroanatomy

The nerves of the small intestines are derived from the plexuses of parasympathetic nerves around the superior mesenteric artery. From this source, they run to the myenteric plexus (Auerbach's plexus) of nerves and ganglia situated between the circular muscular fibers and the longitudinal muscle fibers of the muscularis externa. From this a secondary plexus, the plexus of the submucosa (Meissner's plexus, submucous plexus, submucosal plexus, plexus submucosus) is derived, and it is formed by branches that have perforated the circular muscular fibers. This plexus lies in the submucous coat of the intestine; it also contains ganglia from which nerve fibers pass to the muscularis mucosae and to the mucous membrane.

They contain Dogiel cells.[1] The nerve bundles of the submucous plexus are finer than those of the myenteric plexus. Its function is to innervate cells in the epithelial layer and the smooth muscle of the muscularis mucosae.

14% of submucosal plexus neurons are sensory neurons - Dogiel type II, also known as enteric primary afferent neurones (EPANs) or intrinsic primary afferent neurones (IPANs)).[2] In Auerbach plexus there are 30% of the enteric sensory neurons.


German Georg Meissner was one of the first to further research the nervous system and found Meissners' plexus.


This article incorporates text in the public domain from the 20th edition of Gray's Anatomy (1918)

  1. ^ Stach, W (1979). "[Differentiated vascularization of Dogiel's cell types and the preferred vascularization of type I/2 cells within plexus myentericus (Auerbach) ganglia of the pig (author's transl)].". Anatomischer Anzeiger (in German) 145 (5): 464–73. PMID 507375. 
  2. ^ Anatomy and physiology of the enteric nervous system, M Costa,S J H Brookes,G W Hennig, Gut 2000;47:iv15-iv19 doi:10.1136/gut.47.suppl_4.iv15 ,

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