Melanocortin 5 receptor

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Melanocortin 5 receptor
Identifiers
Symbols MC5R ; MC2
External IDs OMIM600042 MGI99420 HomoloGene4321 IUPHAR: MC5 ChEMBL: 4608 GeneCards: MC5R Gene
RNA expression pattern
PBB GE MC5R 208565 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 4161 17203
Ensembl ENSG00000176136 ENSMUSG00000007480
UniProt P33032 G3UWB6
RefSeq (mRNA) NM_005913 NM_013596
RefSeq (protein) NP_005904 NP_038624
Location (UCSC) Chr 18:
13.82 – 13.83 Mb
Chr 18:
68.34 – 68.34 Mb
PubMed search [1] [2]

Melanocortin receptor 5 is a protein that in humans is encoded by the MC5R gene.[1][2] It is located on the chromosome 18 in the human genome.[2] When the melanocortin 5 receptor was disrupted in transgenic mice, it induced disruption of their exocrine glands and resulted in decreased production of sebum.[3]


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References[edit]

  1. ^ Chhajlani V, Muceniece R, Wikberg JE (Oct 1993). "Molecular cloning of a novel human melanocortin receptor". Biochem Biophys Res Commun 195 (2): 866–73. doi:10.1006/bbrc.1993.2125. PMID 8396929. 
  2. ^ a b "Entrez Gene: MC5R melanocortin 5 receptor". 
  3. ^ Thiboutot, Diane; Sivarajah, Aruntha; Gilliland, Kathryn ; Cong, Zhaoyuan; Clawson, Gary (2000). "The Melanocortin 5 Receptor is Expressed in Human Sebaceous Glands and Rat Preputial Cells". Journal of Investigative Dermatology 115 (4): 614–619. doi:10.1046/j.1523-1747.2000.00094.x. PMID 10998132. Retrieved 2008-01-04. 

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Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.