Memorial Drive, like the parkways along the opposite (Boston) side of the river, is maintained by the Massachusetts Department of Conservation and Recreation (the successor to the Metropolitan District Commission). In keeping with the recreational mission, the section of Memorial Drive from Western Avenue to the split by Mount Auburn Hospital, at Gerry's Landing Road, is closed to motor vehicles on Sundays in the summer to allow for pedestrian and non-motorized users. The closure is in effect from 11:00 am to 7:00 pm starting the last Sunday of April until the second Sunday of November.
A median near Massachusetts Avenue requires executing a so-called Michigan left for certain turns.
In 2003 a two-mile section of Memorial Drive was reconstructed as part of the DCR's Historic Parkways Initiative.