Mepivacaine

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Mepivacaine
Mepivacaine.png
Systematic (IUPAC) name
(RS)-N-(2,6-dimethylphenyl)- 1-methyl-piperidine-2-carboxamide
Clinical data
AHFS/Drugs.com Consumer Drug Information
MedlinePlus a603026
  • C, use w/ caution, may cause fetal bradycardia
Identifiers
96-88-8 YesY
N01BB03
PubChem CID 4062
DrugBank DB00961 YesY
ChemSpider 3922 YesY
UNII B6E06QE59J YesY
KEGG D08181 YesY
ChEBI CHEBI:6759 YesY
ChEMBL CHEMBL1087 YesY
Chemical data
Formula C15H22N2O
246.348 g/mol
 YesY (what is this?)  (verify)

Mepivacaine /mɛˈpɪvəkn/ is a local anesthetic[1] of the amide type. Mepivacaine has a reasonably rapid onset (more rapid than that of procaine) and medium duration of action (shorter than that of procaine) and is marketed under various trade names including Carbocaine and Polocaine.

Mepivacaine became available in the United States in the 1960s.

Mepivacaine is used in any infiltration and regional anesthesia.

It is supplied as the hydrochloride salt of the racemate.[2]

References[edit]

  1. ^ Porto GG, Vasconcelos BC, Gomes AC, Albert D (January 2007). "Evaluation of lidocaine and mepivacaine for inferior third molar surgery" (PDF). Med Oral Patol Oral Cir Bucal 12 (1): E60–4. PMID 17195831. 
  2. ^ Burm AG, Cohen IM, van Kleef JW, Vletter AA, Olieman W, Groen K (January 1997). "Pharmacokinetics of the enantiomers of mepivacaine after intravenous administration of the racemate in volunteers". Anesth. Analg. 84 (1): 85–9. doi:10.1097/00000539-199701000-00016. PMID 8989005. 

External links[edit]