Mepyramine

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Mepyramine
Mepyramine.svg
Systematic (IUPAC) name
N-(4-methoxybenzyl)-N',N'-dimethyl-N-pyridin-2-ylethane-1,2-diamine
Clinical data
AHFS/Drugs.com International Drug Names
MedlinePlus a606008
Legal status ?
Identifiers
CAS number 91-84-9 YesY
59-33-6 (maleate)
ATC code R06AC01 D04AA02
PubChem CID 4992
IUPHAR ligand 1220
DrugBank DB06691
ChemSpider 4818 YesY
UNII HPE317O9TL YesY
KEGG D08183 YesY
ChEBI CHEBI:6762 N
ChEMBL CHEMBL511 YesY
Synonyms N-[2-(dimethylamino)ethyl]-N-[(4-methoxyphenyl)methyl]pyridin-2-amine
Chemical data
Formula C17H23N3O 
Mol. mass 285.38 g/mol
 N (what is this?)  (verify)

Mepyramine, also known as pyrilamine, is a first generation antihistamine, targeting the H1 receptor.[1] However, it rapidly permeates the brain often causing drowsiness. It also has anticholinergic properties. It is used in over-the-counter combination products to treat the common cold and menstrual symptoms.[2] It is also the active ingredient of the topical antihistamine creams Anthisan and Neoantergan, sold for the treatment of insect bites, stings, and nettle rash.

References[edit]

  1. ^ Parsons, Mike E.; Ganellin, C. Robin (January 2006). "Histamine and its receptors". British Journal of Pharmacology 147 (S1): S127–S135. doi:10.1038/sj.bjp.0706440. PMC 1760721. PMID 16402096. 
  2. ^ Active Ingredients for Midol Complete