Its boundaries are the CSXrailroad tracks to the north, Shelby Street to the east, E Brandeis Ave to the south and I-65 to the west. Lincoln Park and Preston Park are located in the neighborhood. It is commonly referred to as part of greater Schnitzelburg. Meriwether is also sometimes confused with Louisville's Germantown neighborhood.
As of 2000, the population of Meriwether was 1,442 , of which 64.9% are white, 29.8% are black, 4.2% are listed as other, & 1% are Hispanic. College graduates are 10.4% of the population, people w/o a high school degree are 23.9%, people with 1+ years of college w/o a degree are 13.6%. Females outnumber males 53% to 47%.