Mesenchyme

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Mesenchyme
Mesenchymal Stem Cell.jpg
Mesenchyme showing a typical cell and matrix.
Mesenchyme.JPG
Mesenchyme (pointer) stained with H&E
Latin mesenchyma
Carnegie stage 6b
Precursor primarily mesoderm
Code TE E5.16.4.0.3.0.18

Mesenchyme is a type of tissue characterized by loosely associated cells that lack polarity and are surrounded by a large extracellular matrix. Mesenchymal cells are able to develop into the tissues of the lymphatic and circulatory systems, as well as connective tissues throughout the body, such as bone and cartilage. A sarcoma is a cancer of mesenchymal cells.[1][2]

Mesenchyme is characterized morphologically by a prominent ground substance matrix containing a loose aggregate of reticular fibrils and unspecialized cells.[3] Mesenchymal cells can migrate easily, in contrast to epithelial cells, which lack mobility and are organized into closely adherent sheets, and are polarized in an apical-basal orientation.

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References[edit]

  1. ^ Strum, Judy M.; Gartner, Leslie P.; Hiatt, James L. (2007). Cell biology and histology. Hagerstwon, MD: Lippincott Williams & Wilkins. p. 83. ISBN 0-7817-8577-4. 
  2. ^ Sadler, T.W. (2006). Langman's Medical Embryology. Lippincott Williams & Wilkins. pp. 68–70. ISBN 0-7817-9485-4. 
  3. ^ Mesenchymal tissue

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