Mestanolone

Mestanolone

Systematic (IUPAC) name
(5α,17β)-17-hydroxy-17-methylandrostan-3-one
Clinical data
AHFS/Drugs.com	International Drug Names
Pregnancy cat.	X (US)
Legal status	DEA Schedule III (US)
Routes	Oral
Pharmacokinetic data
Bioavailability	99% oral
Protein binding	yes
Metabolism	Hepatic
Half-life	?
Excretion	Renal
Identifiers
CAS number	521-11-9 N
ATC code	None
PubChem	CID 10633
ChemSpider	10187 Y
UNII	S712YZ168E Y
KEGG	D01533 Y
ChEMBL	CHEMBL261514 Y
Synonyms	(5S,8R,9S,10S,13S,14S,17S)-17-hydroxy-10,13,17-trimethyl-2,4,5,6,7,8,9,11,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-3-one
Chemical data
Formula	C20H32O2
Mol. mass	304.467 g/mol
SMILES	eMolecules & PubChem
InChI InChI=1S/C20H32O2/c1-18-9-6-14(21)12-13(18)4-5-15-16(18)7-10-19(2)17(15)8-11-20(19,3)22/h13,15-17,22H,4-12H2,1-3H3/t13-,15+,16-,17-,18-,19-,20-/m0/s1 Y Key:WYZDXEKUWRCKOB-YDSAWKJFSA-N Y
N (what is this?)  (verify)

Mestanolone is the 17α-methylated version of dihydrotestosterone (DHT). The systematic name of mestanolone is: 17β-hydroxy-17α-methylandrost-3-one. It is an orally bioavailable androgenic steroid that is highly androgenic while only slightly anabolic. It is incapable of aromatization and is not an agonist of the progesterone receptor.

Dosage Information

Dosages range from 10mg to 30mg a day for males. Women should avoid Mestanolone for it is very androgenic. Long term use, more than 12 weeks should be avoided do to hepatoxicity. Since Mestanolone is unable to convert to estrogen, it is very useful during cutting phases or when one wishes to avoid excess weight gain.