Metampicillin

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Metampicillin
Metampicillin.png
Systematic (IUPAC) name
3,3-Dimethyl-6-[[2-(methylideneamino)-2-phenylacetyl]amino]-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
Clinical data
Identifiers
6489-97-0 YesY
J01CA14
PubChem CID 4084
UNII G0H6U7VSTK N
ChEMBL CHEMBL1908324 N
Chemical data
Formula C17H19N3O4S
361.415 g/mol
 N (what is this?)  (verify)

Metampicillin (INN) is a penicillin antibiotic. It is prepared by the reaction of ampicillin with formaldehyde, and is hydrolysed in aqueous solution with the formation of ampicillin. Hydrolysis is rapid under acid conditions, e.g., in the stomach, less rapid in neutral media, and incomplete in solutions such as human serum.[1]

References[edit]

  1. ^ Sutherland R, Elson S, Croydon EA (1972). "Metampicillin. Antibacterial activity and absorption and excretion in man". Chemotherapy 17 (3): 145–60. doi:10.1159/000220849. PMID 4556172. 

External links[edit]