Methanandamide

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Methanandamide
Methanandamide.svg
Names
IUPAC name
(5Z,8Z,11Z,14Z)-N-[(1R)-2-hydroxy-1-methylethyl]icosa-5,8,11,14-tetraenamide
Other names
AM-356; Arachidonyl-1'-hydroxy-2'-propylamide
Identifiers
157182-49-5 N
ChEMBL ChEMBL120526 YesY
ChemSpider 4881984 YesY
Jmol-3D images Image
PubChem 6321351
Properties
C23H39NO2
Molar mass 361.56 g·mol−1
Except where noted otherwise, data is given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
 N verify (what isYesY/N?)
Infobox references

Methanandamide (AM-356) is a synthetically created stable chiral analog of anandamide.[1] Its effects have been observed to act on the cannabinoid receptors (specifically on CB1 receptors, which are part of the central nervous system) found in different organisms such as mammals, fish, and certain invertebrates (e.g. Hydra).

References[edit]

  1. ^ Abadji, V et al. (1994). "(R)-methanandamide: A chiral novel anandamide possessing higher potency and metabolic stability". Journal of Medical Chemistry 37 (12): 1889–93. doi:10.1021/jm00038a020. PMID 8021930.