Metildigoxin

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Metildigoxin
Medigoxin.png
Systematic (IUPAC) name
(3β,5β,12β)-3-{[2,6-dideoxy-4-O-methyl-β-D-ribo-hexopyranosyl-(1→4)-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-2,6-dideoxy-β-D-ribo-hexopyranosyl]oxy}-12,14-dihydroxycard-20(22)-enolide
Clinical data
AHFS/Drugs.com International Drug Names
Pregnancy
category
  • C
Identifiers
CAS Registry Number 30685-43-9
ATC code C01AA08
PubChem CID: 443946
ChemSpider 392000 YesY
UNII I7GG1YUC5V YesY
Synonyms 4-[(3S,5R,8R,9S,10S,12R,13S,14S)-12,14-Dihydroxy-3-[(2R,4S,5S,6R)-4-hydroxy-5-[(2S,4S,5S,6R)-4-hydroxy-5-[(2S,4S,5S,6R)-4-hydroxy-5-methoxy-6-methyl-oxan-2-yl]oxy-6-methyl-oxan-2-yl]oxy-6-methyl-oxan-2-yl]oxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]-5H-furan-2-one
Chemical data
Formula C42H66O14
Molecular mass 794.965
 YesY (what is this?)  (verify)

Metildigoxin (INN, or medigoxin BAN, or methyldigoxin) is a cardiac glycoside,[1] a type of drug that can be used in the treatment of congestive heart failure and cardiac arrhythmia (irregular heartbeat). The substance is closely related to digoxin; it differs from the latter only by an O-methyl group on the terminal monosaccharide.

References[edit]

  1. ^ Hayward, R.; Greenwood, H.; Stephens, J.; Hamer, J. (1983). "Relationship between myocardial uptake and actions in heart failure of methyldigoxin". British Journal of Clinical Pharmacology 15 (1): 41–48. doi:10.1111/j.1365-2125.1983.tb01461.x. PMC 1427830. PMID 6849743.  edit