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Klaper graduated from the University of Illinois College of Medicine in 1972 and served his medical internship at Vancouver General Hospital with the University of British Columbia. He also studied obstetrics at the University of California in San Francisco.
After graduation, Klaper moved between a number of locations, practiced acute care medicine, and eventually became certified in urgent care medicine. Following a desire to lead a less violent life, Klaper became a vegan in the early 1980s.
He served as director of a vegan health spa in Pompano Beach, Florida from the early 1990s and was featured on the PBS documentary Diet For A New America by John Robbins. He returned to medical practice in Maui, Hawaii, between 1995 and 2006, and Whangarei, New Zealand, between 2006 and 2009. In 2010, he returned to nutritional medicine and currently serves on the medical staff at the TrueNorth Health Center in Santa Rosa, California.
His books include Vegan Nutrition: Pure and Simple and Pregnancy, Children, and the Vegan Diet.
- Klaper, Michael (2000) . Vegan Nutrition: Pure and Simple (4th ed.). Kapaau, Hawaii: Gentle World. ISBN 9780929274232.
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