|Classification and external resources|
Microcytic anaemia is a generic term for any type of anemia characterized by small red blood cells. The normal mean corpuscular volume (abbreviated to MCV on full blood count results) is 76-100 fL, with smaller cells (<76 fL) described as microcytic and larger cells (>100 fL) as macrocytic.
In microcytic anemia, the red blood cells (erythrocytes) are usually also hypochromic, meaning that the red blood cells are paler than usual. This can be quantified as the mean corpuscular hemoglobin or mean cell hemoglobin (MCH), the amount of hemoglobin per cell; the normal value is 27-32 picograms (pg). Similar is the mean corpuscular hemoglobin concentration (MCHC), giving the amount of hemoglobin per volume of erythrocytes (normally about 320-360 g/L or 32-36 g/dL). Typically, therefore, anemia of this category is described as "microcytic, hypochromic anemia".
Typical causes of microcytic anemia include:
- Iolascon A, De Falco L, Beaumont C (January 2009). "Molecular basis of inherited microcytic anemia due to defects in iron acquisition or heme synthesis". Haematologica 94 (3): 395–408. doi:10.3324/haematol.13619. PMC 2649346. PMID 19181781.
- Weng, CH; Chen JB, Wang J, Wu CC, Yu Y, Lin TH (2011). "Surgically Curable Non-Iron Deficiency Microcytic Anemia: Castleman's Disease.". Onkologie 34 (8-9): 456–8. doi:10.1159/000331283. PMID 21934347.