All clubs from the Middle Rhine playing in the 3. Liga (III) and the Regionalliga West (IV) are directly qualified for the first round, the remaining places are filled with the teams who qualified from local cup competitions, the Kreispokale. All up, 32 clubs take part in the first round of the competition.
Since the establishment of the 3. Liga in 2008, reserve teams can not take part in the German Cup or the Middle Rhine Cup anymore.