Midgut

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Midgut
Illu small intestine.jpg
The midgut and hindgut.
Details
Latin Mesenteron
Carnegie stage 10
Mesenchyme
Identifiers
Code TE E5.4.7.0.0.0.2
Anatomical terminology

The midgut is the portion of the embryo from which most of the intestines develop. After it bends around the superior mesenteric artery, it is called the "midgut loop". It comprises the portion of the alimentary canal from the end of the foregut at the opening of the bile duct to the hindgut, about two-thirds of the way through the transverse colon.

Physiological herniation of the midgut in development[edit]

During development, the human midgut undergoes a rapid phase of growth in which the loop of midgut herniates outside of the abdominal cavity of the fetus and protrudes into the umbilical cord. This herniation is physiological (occurs normally). Later in development, the fetus's body catches up in size relative to the size of its own midgut and thereby creates adequate room in the abdominal cavity for the entirety of the midgut to reside. Thus, the midgut loops slips back out of the umbilical cord and the physiological hernia ceases to exist. This change coincides with the termination of the yolk sac and the counterclockwise rotation of the two limbs of the midgut loop around their combined central axis.[1]

There exist certain diseases in which this physiological hernia does not spontaneously resolve, thus creating pathology. The most common of these is omphalocele. In omphalocele, there is a defect in the development of the anterior abdominal wall. Thus, a permanent outpouching of peritoneum through the umbilicus exists, unless surgically corrected.

Structures in the adult midgut[edit]

Vascular, lymphatics and innervation[edit]

Arterial supply to the midgut is from the superior mesenteric artery, an unpaired branch of the aorta. Venous drainage is to the portal venous system. Lymph from the midgut drains to prevertebral superior mesenteric nodes located at the origin of the superior mesenteric artery from the aorta. Portal drainage carries all non-lipid nutrients from digestion to the liver for processing and detoxification, while lymphatic drainage carries fatty chyle to the cisterna chyli. Autonomic innervation of the midgut is from the superior mesenteric plexus.

Clinical relevance[edit]

  • Malrotation of the midgut during development can lead to volvulus.
  • Pain in the midgut is referred to the umbilical region (around the umbilicus (belly button)).

See also[edit]

References[edit]

  1. ^ Drake, Richard L., et al. Gray's anatomy for students. Philadelphia, PA: Churchill Livingstone/Elsevier, 2010, p. 259

External links[edit]