Mikk Mikiver graduated from the State Conservatory of Tallinn in 1961. He then went on to appear in many Estonian films and was a highly regarded dramatic actor. In addition to stage and film, Mikiver was also a prodigious television actor. While never retiring from acting, Mikiver gradually became more interested in theater direction and was for many years the principal director of the Estonian Drama Theater and the Estonian Youth Theater.
For his notable achievements, the Estonian government awarded Mikiver the Order of the White Star, 4th Class, as well as the National Lifetime Achievement award. Mikiver was also a patron of the Tallinn Children's Hospital Foundation. He died at the age of 68 on January 9, 2006.
Mikk Mikiver was the older brother of actor Tõnu Mikiver and was married to Carmen Mikiver.