Miotine
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| Miotine | |
|---|---|
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[3-[1-(Dimethylamino)ethyl]phenyl] N-methylcarbamate |
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| Identifiers | |
| CAS number | 4464-16-8 |
| PubChem | 46093 |
| Jmol-3D images | Image 1 |
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| Properties | |
| Molecular formula | C12H18N2O2 |
| Molar mass | 222.28 g mol−1 |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) |
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| Infobox references | |
Miotine is an anticholinesterase drug. Miotine was the first synthetic carbamate that was used clinically.[1]
Unlike the miotine analog neostigmine, it doesn't have a quaternary ammonium group to give it a permanent positive charge. It can exist as an uncharged free base which could allow it to cross the blood–brain barrier and cause unwanted central nervous system (CNS) side effects.[2]
References [edit]
- ^ "http://www.weizmann.ac.il/sb/faculty_pages/Sussman/papers/2002_Bar-On_Biochem.pdf"
- ^ "http://media.wiley.com/product_data/excerpt/72/04700259/0470025972.pdf"
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