Missouri Route 80

Route 80
Route information
Maintained by MoDOT
Length	27.302 mi (43.938 km)
Major junctions
West end	US 61 / US 62 / Route H south of Sikeston
East end	Dead End at the Mississippi River in Belmont
Location
Country	United States
State	Missouri
Highway system
Missouri State Highway System Interstate US State Supplemental
← Route 79 → Route 81

Route 80 is a highway in southeastern Missouri. Its eastern terminus is at the Mississippi River in Belmont; its western terminus is at U.S. Route 61/U.S. Route 62 midway between Sikeston and New Madrid. East Prairie is the only other town on the highway.

At Belmont, there used to be a ferry connecting Route 80 to Kentucky Route 80, which is a major east–west thoroughfare across southern Kentucky, continuing into Virginia, as Virginia State Route 80.

Major intersections

Route 80 in East Prairie

County	Location	mi	km	Destinations	Notes
New Madrid	​	0.000	0.000	US 61 / US 62 / Route H – Matthews, New Madrid, Sikeston	Western terminus; Eastern terminus of Route H
	​	1.505– 1.596	2.422– 2.569	I-55 – Sikeston, Blytheville, AR	Diamond interchange
	​	1.634	2.630	Route V	Northern terminus of Route V
	​	2.566	4.130	Route AA – Miner	Southern terminus of Route AA
New Madrid–Mississippi county line	​	8.058	12.968	Route B – Bertrand	Southern terminus of Route B
Mississippi	​	10.052	16.177	Route BB	Northern terminus of Route BB
	East Prairie	11.171	17.978	Route 105 – Charleston	Southern terminus of Route 105
	​	13.236	21.301	Route 102 – Charleston
	​	15.263	24.563	Route 75 – Anniston	Southern terminus of Route 75
	​	17.817	28.674	Route AA	Northern terminus of Route AA
	​	21.312	34.298	Route 77 – Wyatt, Wolf Island
	​	27.302	43.938	Belmont–Columbus Ferry	Former ferry, currently a dead end
1.000 mi = 1.609 km; 1.000 km = 0.621 mi       Closed/former