The book serves as a eulogy for psychologist and psychedelic drug researcher/advocate Timothy Leary (1920–1996). It contains an obituary Thompson wrote for Leary that first appeared in Rolling Stone Magazine. The book also contains a simulated blotter sheet on which Dr. Leary's likeness is printed and other Leary-related artifacts.
The book was hand-sewn and hand-printed at The New Orleans School of GlassWorks and Printmaking Studio, with a print run of only 300 hand-numbered copies. In addition, 26 special lettered copies were also produced.