Mitochondrial fusion

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Mitochondria can join by fusion. Several protein ensembles that are involved in mitochondrial fusion have been characterized.


There is a mitochondrial outer membrane fusion machinery, composed by proteins of the Fzo1 family in yeast or by MFN1, MFN2 in mammals, and a mitochondrial inner membrane fusion machinery, with the Mgm1 protein in yeast or the equivalent OPA1 in mammals.[1]

See also[edit]


  1. ^ Hoppins, S.; Lackner, L.; Nunnari, J. (2007). "The Machines that Divide and Fuse Mitochondria". Annual Review of Biochemistry 76: 751–780. doi:10.1146/annurev.biochem.76.071905.090048. PMID 17362197.  edit