Born in Granja, Ceará, Mitotônio began playing club football for Fortaleza Esporte Clube. He joined Ceará in 1941 and would win three Ceará state championships during his 10 years with the club. He also had a brief spell with Náutico in 1945.
On 31 March 1951, Mitotônio became ill during the first half of Ceará's Campeonato Cearense match against Gentilândia at Estádio Presidente Vargas. He scored the opening goal for Ceará, but did not play in the second half. The team sent Mitotônio to hospital where he was released in the evening after treatment. He died the following morning at his home at age 35. He death was attributed to a hemorrhage resulting from stomach congestion.