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Miyoshi Yoshitsugu (三好 義継, 1549 - December 10, 1573), adopted son of Nagayoshi, was a samurai of the Sengoku period who was practically the last head of Miyoshi clan, daimyo of Kawachi province of Japan.
Born to Sogō Kazumasa, younger brother of Miyoshi Nagayoshi, he was initially known as Sogō Shigemasa (十河 重存). After 1561 when his father died, he was reared by Nagayoshi. When Nagayoshi's eldest son Yoshioki died in 1563, he was adopted as a son and changed his surname to Miyoshi. The following year when Nagayoshi died, Yoshitsugu succeeded him as head of the clan.
Nagamoto is his son.
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