On or about October 12, 1942, the ghetto of about 1,700 people was surrounded by Ukrainian auxiliaries and German policemen in preparation for the liquidation of its Jewish occupants. The Jews fought back in a defense which may have lasted as long as two days. About half the residents were able to flee or hide during the confusion before the uprising was finally put down. On October 14, the captured survivors were taken to a ravine and shot. 
The shootings were photographed. The photographs were published and have become well known. Frequently the photographs are said to depict other shootings. Historians have commented upon the brutality shown in the Mizocz shooting photographs:
In 1942 at Mizocz, in the region of Rovno in Ukraine, approximately 1,700 Jews were executed. The photographs show large numbers of people being herded into a ravine, women and children undressing, a line of naked women and children in a queue and finally their executed bodies. Two particular harrowing photographs show German police standing among heaps of naked corpses of women strewn on either side of the ravine.
Further, two of the photographs show the "Aktion" in progress. The photographs give clear evidence of the execution practice, common in Ukraine, of bringing the victims to the killing site in small groups of around five or so individuals, and having them lie down among the prior victims, to be shot in the back of the neck or head with a single bullet.
Huneke, Douglas K., The Moses of Rovno: the stirring story of Fritz Graebe, a German Christian who risked his life to lead hundreds of Jews to safety during the Holocaust, New York, Dodd, Mead, 1985 ISBN 0-396-08714-0