Molecular Biology of the Cell (textbook)

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Molecular Biology of the Cell
Peter Walter, Julian Lewis, Alexander Johnson, Martin Raff - from Flickr 2195862704.jpg
Authors Peter Walter, Julian Lewis, Alexander Johnson and Martin Raff (from left to right)
Author Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter
Subject Cell biology
Publisher Garland Science
Publication date
December 2007
Pages 1392 pp (fifth edition)
ISBN ISBN 978-0-8153-4105-5 (hardcover), ISBN 978-0-8153-4106-2 (softcover)
571.6 22
LC Class QH581.2 .M64 2008

Molecular Biology of the Cell is a cellular and molecular biology textbook published by Garland Science and currently authored by Bruce Alberts, Alexander Johnson, Julian Lewis (died 2014), Martin Raff, Keith Roberts and Peter Walter. The book was first published in 1983 and is now in its fifth edition. James Watson contributed to the first three editions.

Molecular Biology of the Cell is widely used in introductory courses at the university level, being considered as a reference in many libraries and laboratories around the world. It describes the current understanding of cell biology and includes basic biochemistry, experimental methods for investigating cells, the properties common to most eukaryotic cells, the expression and transmission of genetic information, the internal organization of cells, and the behaviour of cells in multicellular organisms.[1] The latest fifth edition, published in 2007, has been updated to include recent advancements in the field of cell biology, including epigenetics, stem cells, RNAi, comparative genomics and the latest cancer therapies.[2] Importantly, Molecular Biology of the Cell has been described as “the most influential cell biology textbook of its time”.[3]

The fourth edition can be searched at the National Center for Biotechnology Information bookshelf.

Work on the sixth edition has been underway since late 2010,[4] and it will be published on December 1st, 2014.[5]

Table of contents[edit]

Part I - Introduction to the Cell

1. Cells and Genomes

2. Cell Chemistry and Biosynthesis

3. Proteins

Part II - Basic Genetic Mechanisms

4. DNA, Chromosomes, and Genomes

5. DNA Replication, Repair, and Recombination

6. How Cells Read the Genome: From DNA to Protein

7. Control of Gene Expression

Part III - Methods

8. Manipulating Proteins, DNA, and RNA

9. Visualizing Cells

Part IV Internal Organization of the Cell

10. Membrane Structure

11. Membrane Transport of Small Molecules and the Electrical Properties of Membranes

12. Intracellular Compartments and Protein Sorting

13. Intracellular Vesicular Traffic

14. Energy Conversion: Mitochondria and Chloroplasts

15. Mechanisms of Cell Communication

16. The Cytoskeleton

17. The Cell Cycle

18. Apoptosis

Part V - Cells in their Social Context

19. Cell Junctions, Cell Adhesion, and the Extracellular Matrix

20. Cancer Chapters

21. Sexual Reproduction: Meiosis, Germ Cells, and Fertilization

22. Development of Multicellular Organisms

23. Specialized Tissues, Stem Cells, and Tissue Renewal

24. Pathogens, Infection, and Innate Immunity

25. The Adaptive Immune System


External links[edit]