A molecular cloud, sometimes called a stellar nursery if star formation is occurring within, is a type of interstellar cloud whose density and size permits the formation of molecules, most commonly molecular hydrogen (H2). This is in contrast to other areas of the interstellar medium that contain predominately ionized gas.
Molecular hydrogen is difficult to detect by infrared and radio observations, so the molecule most often used to determine the presence of H2 is CO (carbon monoxide). The ratio between CO luminosity and H2 mass is thought to be constant, although there are reasons to doubt this assumption in observations of some other galaxies.
Within our own galaxy, molecular gas clouds accounts for less than one percent of the volume of the interstellar medium (ISM), yet it is also the densest part of the medium comprising roughly one-half of the total gas mass interior to the Sun's galactic orbit. The bulk of the molecular gas is contained in a ring between 3.5 and 7.5 kiloparsecs (11,000 and 24,000 ly) from the center of the galaxy (the Sun is about 8.5 kpc from the center). Large scale carbon monoxide maps of the galaxy show that the position of this gas correlates with the spiral arms of the galaxy. That molecular gas occurs predominantly in the spiral arms argues that molecular clouds must form and dissociate on a timescale shorter than 10 million years—the time it takes for material to pass through the arm region.
Vertically to the plane of the galaxy, the molecular gas inhabits the narrow midplane of the Galactic disc with a characteristic scale height, Z, of approximately 50–75 parsec, much thinner than the warm atomic (Z=130–400 pc) and warm ionized (Z=1000 pc) gaseous components of the ISM. The exception to the ionized gas distribution are HII regions which are bubbles of hot ionized gas created in molecular clouds by the intense radiation given off by young massive stars and as such they have approximately the same vertical distribution as the molecular gas.
This distribution of molecular gas is averaged out over large distances; however, the small scale distribution of the gas is highly irregular with most of it concentrated in discrete clouds and cloud complexes.
Types of molecular cloud 
Giant molecular clouds (GMCs) 
A vast assemblage of molecular gas with a mass of approximately 103–107 times the mass of the Sun is called a giant molecular cloud (GMC). GMCs are ≈15–600 light-years in diameter (5–200 parsecs). Whereas the average density in the solar vicinity is one particle per cubic centimetre, the average density of a GMC is a hundred to a thousand times as great. Although the Sun is much denser than a GMC, the volume of a GMC is so great that it contains much more mass than the Sun. The substructure of a GMC is a complex pattern of filaments, sheets, bubbles, and irregular clumps.
The densest parts of the filaments and clumps are called "molecular cores", whilst the densest molecular cores are called "dense molecular cores" and have densities in excess of 104–106 particles per cubic centimeter. Observationally molecular cores are traced with carbon monoxide and dense cores are traced with ammonia. The concentration of dust within molecular cores is normally sufficient to block light from background stars so that they appear in silhouette as dark nebulae.
GMCs are so large that "local" ones can cover a significant fraction of a constellation; thus they are often referred to by the name of that constellation, e.g. the Orion Molecular Cloud (OMC) or the Taurus Molecular Cloud (TMC). These local GMCs are arrayed in a ring in the neighborhood of the Sun coinciding with the Gould Belt. The most massive collection of molecular clouds in the galaxy forms an asymmetrical ring about the galactic center at a radius of 120 parsecs; the largest component of this ring is the Sagittarius B2 complex. The Sagittarius region is chemically rich and is often used as an exemplar by astronomers searching for new molecules in interstellar space.
Small molecular clouds 
Isolated gravitationally-bound small molecular clouds with masses less than a few hundred times that of the Sun are called Bok globules. The densest parts of small molecular clouds are equivalent to the molecular cores found in GMCs and are often included in the same studies.
High-latitude diffuse molecular clouds 
In 1984 IRAS identified a new type of diffuse molecular cloud. These were diffuse filamentary clouds that are visible at high galactic latitudes. These clouds have a typical density of 30 particles per cubic centimeter.
Star formation 
The general hypothesis is that the creation of stars occurs exclusively within molecular clouds. This is a natural consequence of their low temperatures and high densities, since the gravitational force acting to collapse the cloud may exceed the internal pressures that are acting "outward" to prevent a collapse. There is observed evidence that the large, star-forming clouds are confined to a large degree by their own gravity (like stars, planets, and galaxies) rather than by external pressure. The evidence comes from the fact that the "turbulent" velocities inferred from CO linewidth, scale in the same manner as the orbital velocity (a virial relation).
The physics of molecular clouds are poorly understood and much debated. Their internal motions are governed by turbulence in a cold, magnetized gas, for which the turbulent motions are highly supersonic but comparable to the speeds of magnetic disturbances. This state is thought to lose energy rapidly, requiring either an overall collapse or a steady reinjection of energy. At the same time, the clouds are known to be disrupted by some process—most likely the effects of massive stars—before a significant fraction of their mass has become stars.
Molecular clouds, and especially "giant" molecular clouds (GMCs), are often the home of astronomical masers.
See also 
- Interstellar ice
- Orion Molecular Cloud Complex
- Atomic and molecular astrophysics
- List of interstellar and circumstellar molecules
- Evaporating gaseous globule
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