Muir–Torre syndrome
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(Redirected from Muir-Torre syndrome)
| Muir–Torre syndrome | |
|---|---|
| Classification and external resources | |
 Micrograph of a sebaceous adenoma, as may be seen in Muir-Torre syndrome. H&E stain. |
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| OMIM | 158320 |
| DiseasesDB | 31385 |
| eMedicine | derm/275 |
| MeSH | D055653 |
Muir–Torre syndrome (MTS) is an inherited cancer syndrome[1]:663 that is thought to be a subtype of HNPCC. Individuals are prone to develop cancers of the colon, breast and genitourinary tract, and skin lesions, such as keratoacanthomas and sebaceous tumours. The genes affected are MLH1 & MSH2, and involved in DNA mismatch repair.
[edit] Eponym
It is named for EG Muir and D Torre.[2][3]
[edit] References
- ^ James, William D.; Berger, Timothy G.; et al. (2006). Andrews' Diseases of the Skin: clinical Dermatology. Saunders Elsevier. ISBN 0-7216-2921-0.
- ^ Muir EG, Bell AJ, Barlow KA (March 1967). "Multiple primary carcinomata of the colon, duodenum, and larynx associated with kerato-acanthomata of the face". Br J Surg 54 (3): 191–5. doi:10.1002/bjs.1800540309. PMID 6020987.
- ^ Torre D (November 1968). "Multiple sebaceous tumors". Arch Dermatol 98 (5): 549–51. doi:10.1001/archderm.98.5.549. PMID 5684233.
[edit] External links
- Muir–Torre syndrome - Victoria Infirmary
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