Musculoskeletal injury (MI, not to be confused with myocardial infarction) refers to damage of muscular or skeletal systems, which is usually due to a strenuous activity. In one study, roughly 25% of approximately 6300 adults received a musculoskeletal injury of some sort within 12 months—of which 83% were activity-related. MI spans into a large variety of medical specialties including orthopedic surgery (with diseases such as arthritis requiring surgery), emergency medicine (acute presentations of joint and muscular pain) and rheumatology (in rheumatological diseases that affect joints such as rheumatoid arthritis). In many cases, during the healing period after a Musculoskeletal injury, a period in which the healing area will be completely immobile, a cast-induced muscle atrophy can occur. Routine sessions of physiotherapy after the cast is removed can help return strength in limp muscles or tendons. Alternately, there exist different methods of electrical stimulation of the immobile muscles which can be induced by a device placed underneath a cast, helping prevent atrophies. 
- Hootman JM, Macera CA, Ainsworth BE, Addy CL, Martin M, Blair SN (May 2002). "Epidemiology of musculoskeletal injuries among sedentary and physically active adults". Med Sci Sports Exerc 34 (5): 838–44. doi:10.1097/00005768-200205000-00017. PMID 11984303. Retrieved 2008-08-04.
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