Muzolimine

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Muzolimine
Muzolimine.png
Systematic (IUPAC) name
5-amino-2-[1-(3,4-dichlorophenyl)ethyl]-4H-pyrazol-3-one
Clinical data
Legal status
  • Withdrawn
Identifiers
ATC code C03CD01
PubChem CID 41386
ChemSpider 37766
UNII 07Z36289ZX YesY
KEGG D05093 YesY
Chemical data
Formula C11H11Cl2N3O 
Mol. mass 272.13 g/mol
 YesY (what is this?)  (verify)

Muzolimine is a loop diuretic.[1] It is a pyrazole diuretic which was used for treatment of hypertension but was withdrawn worldwide because of severe neurological side effects.[2]

References[edit]

  1. ^ Wangemann, P.; Braitsch, R.; Greger, R. (1987). "The diuretic effect of muzolimine". Pflugers Archiv : European journal of physiology 410 (6): 674–676. PMID 3449804.  edit
  2. ^ Reyes, A. J.; Leary, W. P. (1993). "Clinicopharmacological reappraisal of the potency of diuretics". Cardiovascular Drugs and Therapy 7: 23–28. doi:10.1007/BF00877955. PMID 8435374.  edit