Kusonoki and Ezaki 1992 ATCC 19977
Mycobacterium abscessus is a rapidly growing mycobacterium that is a common water contaminant. It was until recently (1992) thought to be a subspecies of Mycobacterium chelonae. M. abscessus can cause chronic lung disease, post-traumatic wound infections, and disseminated cutaneous diseases, mostly in patients with suppressed immune systems.
M. abscessus cells are Gram-positive, nonmotile, acid-fast rods of about 1.0 - 2.5 µm long by 0.5 µm wide. They may form colonies on Löwenstein-Jensen media that appear smooth or rough, white or greyish and nonphotochromogenic.
M. abscessus shows growth at 28°C and 37°C after 7 days but not at 43°C. It may grow on MacConkey agar at 28°C and even 37°C. It shows tolerance to saline media (5% NaCl) as well as 500 mg/l hydroxylamine (Ogawa egg medium) and 0.2% picrate (Sauton agar medium). Strains of the species have been shown to degrade the antibiotic p-aminosalicylate. M. abscessus has also been shown to produce arylsulfatase but not of nitrate reductase and Tween 80 hydrolase. It shows a negative result for the iron uptake test and no utilisation of fructose, glucose, oxalate or citrate as sole carbon sources.
Differential characteristics 
M. abscessus and M. chelonae can be distinguished from M. fortuitum or M. peregrinum by their failure to reduce nitrate and to take up iron. Tolerance to 5% NaCl in Löwenstein-Jensen media, tolerance to 0.2% picrate in Sauton agar, and non-utilisation of citrate as a sole carbon source are characteristics that distinguish M. abscessus from M. chelonae. M. abscessus and M. chelonae sequevar I share an identical sequence in the 54-510 region of 16S rRNA, though both species can be differentiated by their hsp65, ITS or rpoB gene sequences.
M. abscessus may cause chronic lung disease, post-traumatic wound infections, and skin infections in immunodeficient patients.
Type strain 
ATCC 19977 = CCUG 20993 = CIP 104536 = DSM 44196 = JCM 13569 = NCTC 13031
- Esteban J, Ortiz-Pérez A (December 2009). "Current treatment of atypical mycobacteriosis". Expert Opin Pharmacother 10 (17): 2787–99. doi:10.1517/14656560903369363. PMID 19929702.
- Linmans JJ, Stokroos RJ, Linssen CF (September 2008). "Mycobacterium abscessus, an uncommon cause of chronic otitis media: a case report and literature review". Arch. Otolaryngol. Head Neck Surg. 134 (9): 1004–6. doi:10.1001/archotol.134.9.1004. PMID 18794448.
- Kusunoki,S.,T. Ezaki. 1992. Proposal of Mycobacterium peregrinum sp. nov., nom. rev., and elevation of Mycobacterium chelonae subsp. abscessus (Kubica et al.) to species status: Mycobacterium abscessus comb. nov. Int. J. Syst. Bacteriol. 42, 240-245.
|This Mycobacterium article is a stub. You can help Wikipedia by expanding it.|