Mycobacterium kansasii

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Mycobacterium kansasii
Scientific classification
Kingdom: Bacteria
Phylum: Actinobacteria
Order: Actinomycetales
Suborder: Corynebacterineae
Family: Mycobacteriaceae
Genus: Mycobacterium
Species: M. kansasii
Binomial name
Mycobacterium kansasii
Hauduroy 1955,[1] ATCC 12478

Mycobacterium kansasii is a bacterium in the Mycobacterium family. The genus includes species known to cause serious diseases in mammals, including tuberculosis and leprosy,[2] but this species is generally not dangerous to healthy people.

Description[edit]

Gram-positive, nonmotile, moderately long to long and acid-fast rods.

Colony characteristics

  • Smooth to rough colonies after 7 or more days of incubation.
  • Colonies grown in dark are nonpigmented, when grown in light or when young colonies are exposed briefly to light, colonies become brilliant yellow (photochromogenic).
  • If grown in a lighted incubator, most strains form dark red crystals of β-carotene on the surface and inside of colony.

Physiology

Differential characteristics

  • Closely related to the non-pathogenic, also slowly growing, nonpigmented, M. gastri.
  • Both species share an identical 16S rDNA but differentiation is possible by differences in the ITS and hsp65 sequences
  • A commercial hybridisation assay (AccuProbe) to identify M. kansasii exists.

Pathogenesis[edit]

Type strain[edit]

  • First and most frequently isolated from human pulmonary secretions and lesions.

Strain ATCC 12478 = CIP 104589 = DSM 44162 = JCM 6379 = NCTC 13024.

References[edit]

  1. ^ Hauduroy, P. (1955). Derniers aspects du monde des mycobactéries. Paris: Masson et Cie. OCLC 876707134. 
  2. ^ Ryan KJ; Ray CG, eds. (2004). Sherris Medical Microbiology (4th ed.). McGraw Hill. ISBN 0-8385-8529-9. 
  3. ^ Mycobacterium Kansasii at eMedicine
  4. ^ Wintrobe, Maxwell Myer (2004). Wintrobe's clinical hematology. John G. Greer; John Foerster, John N. Lukens, George M Rodgers, Frixos Paraskevas (11 ed.). Hagerstown, MD: Lippincott Williams & Wilkins. p. 2467. ISBN 0-7817-3650-1. 
  5. ^ James, William D.; Berger, Timothy G.; et al. (2006). Andrews' Diseases of the Skin: clinical Dermatology. Saunders Elsevier. ISBN 0-7216-2921-0. 

External Links[edit]