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Reed 1957, ATCC 19422
- Member of the Mycobacterium tuberculosis complex (MTBC)
- Also known as the 'Vole bacillus'
- Etymology: microtus is a genus that includes the vole.
- Variable colony morphology, buff in colour, either rough or smooth.
- Growth on glycerol-free egg media at 37°C within 28–60 days. May adapt tolerance to glycerol.
- Sensitive to isoniazid, ethambutol, rifampin, streptomycin and pyrazinamide.
- A commercial hybridisation assay (AccuProbe) to identify members of the M. tuberculosis complex exists.
- All members of the M. tuberculosis complex share identical 16S rDNA and internal transcribed spacers (ITS) sequences
- But molecular differentiation is possible by gyrB sequence polymorphism
- Cause of naturally acquired generalized tuberculosis in voles.
- Recently van Soolingen et al. reported about the first infections among humans caused by M. microti
- Losing pathogenicity on repeated subculture.
- Biosafety level 3
Strain ATCC 19422 = CIP 104256 = NCTC 8710.
- Reed, G. (1957). "Genus Mycobacterium (species affecting warm-blooded animals except those causing leprosy)". In Breed, R.S.; Murray, E.G.D.; Smith, N.R. Bergey's Manual of Determinative Bacteriology (7th ed.). Baltimore: Williams & Wilkins. pp. 703–4.
- van Soolingen D, van der Zanden AG, de Haas PE et al. (July 1998). "Diagnosis of Mycobacterium microti infections among humans by using novel genetic markers". J. Clin. Microbiol. 36 (7): 1840–5. PMC 104938. PMID 9650922.
- "Mycobacterium microti". NCBI Taxonomy Browser. 1806.
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