Mycobacterium montefiorense

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Mycobacterium montefiorense
Scientific classification
Kingdom: Bacteria
Phylum: Actinobacteria
Order: Actinomycetales
Suborder: Corynebacterineae
Family: Mycobacteriaceae
Genus: Mycobacterium
Species: M. montefiorense
Binomial name
Mycobacterium montefiorense
Levi et al. 2003, ATCC BAA-256

Mycobacterium montefiorense has been demonstrated to be an etiologic agent of a granulomatous skin disease of moray eels.[citation needed] Sequence analysis, of the 16S rRNA gene reveals M. montefiorense is most closely related to Mycobacterium triplex, an opportunistic pathogen of humans.

M. montefiorense was named after the Montefiore Medical Center, Bronx, N.Y., the medical institution where it was isolated.

Description[edit]

Microscopy reveals beaded acid-fast rods from growth on Middlebrook 7H10 media at 25°C

The colony characteristics are such that growth from Middlebrook 7H10 media at 25°C has small and transparent, slow growing, nonchromogenic colonies.

The physiology is such that it does not grow at temperatures of >30°C.

The differential characteristics are the following:

  • Unique 16S rRNA gene with its closest match being M. triplex
  • Sequences of the hsp65 amplicon demonstrated that M. montefiorense differs from M. triplex by 10 of 441 nucleotides and M. genavense by 14 of 441 nucleotides of the hsp65 gene sequence.

Pathogenesis[edit]

M. montefiorense has been demonstrated to cause granulomatous skin disease of moray eels.

Type strain[edit]

The strain ATCC BAA-256 = CCUG 51898 = DSM 44602.

References[edit]

  • Levi et al. 2003. Characterization of Mycobacterium montefiorense sp. nov., a novel pathogenic mycobacterium from moray eels that is related to Mycobacterium triplex. J. Clin. Microbiol., 41, 2147-2152.