N-Acetylgalactosamine
| N-Acetylgalactosamine | |
|---|---|
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2-(Acetylamino)-2-deoxy-D-galactose |
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Other names
GalNAc; 2-Acetamido-2-deoxy-D-galactose; N-Acetylchondrosamine; 2-Acetamido-2-deoxy-D-galactopyranose; N-Acetyl-D-galactosamine |
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| Identifiers | |
| CAS number | 31022-50-1 |
| PubChem | 84265 |
| ChemSpider | 76020 |
| ChEBI | CHEBI:40356 |
| Jmol-3D images | Image 1 |
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| Properties | |
| Molecular formula | C8H15NO6 |
| Molar mass | 221.21 g/mol |
| Melting point |
172–173 °C |
| Hazards | |
| S-phrases | S24/25 |
| Related compounds | |
| Related monosaccharides | N-Acetylglucosamine Galactosamine Galactose |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) |
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| Infobox references | |
N-Acetylgalactosamine (GalNAc), is an amino sugar derivative of galactose.
[edit] Function
In humans it is the terminal carbohydrate forming the antigen of blood group A.[1]
It is typically the first monosaccharide that connects serine or threonine in particular forms of protein O-glycosylation.
N-Acetylgalactosamine is necessary for intercellular communication, and is concentrated in sensory nerve structures of both humans and animals.
[edit] See also
[edit] References
- ^ Donald M. Marcus, Elvin A. Kabat, Gerald Schiffman (1964). "Immunochemical Studies on Blood Groups. XXXI. Destruction of Blood Group A Activity by an Enzyme from Clostridium tertium Which Deacetylates N-Acetylgalactosamine in Intact Blood Group Substances". Biochemistry 3: 437–443. doi:10.1021/bi00891a023. http://pubs.acs.org/doi/abs/10.1021/bi00891a023.