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Skeletal formula of n-butylamine
Abbreviations NBA
CAS number 109-73-9 YesY
PubChem 8007
ChemSpider 7716 YesY
EC number 203-699-2
UN number 1125
DrugBank DB03659
MeSH n-butylamine
RTECS number EO29750002
Beilstein Reference 605269
Gmelin Reference 1784
Jmol-3D images Image 1
Molecular formula C4H11N
Molar mass 73.14 g mol−1
Appearance Colorless liquid
Odor fishy, ammoniacal
Density 740 mg mL−1
Melting point −49 °C; −56 °F; 224 K
Boiling point 77 to 79 °C; 170 to 174 °F; 350 to 352 K
Solubility in water Miscible
log P 1.056
Vapor pressure 9.1 kPa (at 20 °C)
kH 570 μmol Pa−1 kg−1
Refractive index (nD) 1.401
Viscosity 500 μPa s (at 20 °C)
heat capacity
188 J K−1 mol−1
Std enthalpy of
−128.9–−126.5 kJ mol−1
Std enthalpy of
−3.0196–−3.0174 MJ mol−1
MSDS hazard.com
GHS pictograms The flame pictogram in the Globally Harmonized System of Classification and Labelling of Chemicals (GHS) The corrosion pictogram in the Globally Harmonized System of Classification and Labelling of Chemicals (GHS) The exclamation-mark pictogram in the Globally Harmonized System of Classification and Labelling of Chemicals (GHS)
GHS signal word DANGER
GHS hazard statements H225, H302, H312, H314, H332
GHS precautionary statements P210, P280, P305+351+338, P310
EU Index 612-005-00-0
EU classification Highly Flammable F Corrosive C
R-phrases R11 R20/21/22, R35
S-phrases S3, S16, S26, S29 S36/37/39 S45
Flash point −7 °C (19 °F; 266 K)
Explosive limits 1.7–9.8%
  • 366 mg kg−1 (oral, rat)
  • 626 mg kg−1 (dermal, rabbit)
Related compounds
Related alkanamines
Related compounds 2-Methyl-2-nitrosopropane
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
 N (verify) (what is: YesY/N?)
Infobox references

n-Butylamine is an organic compound (specifically, an amine) with the formula CH3CH2CH2CH2NH2. This colourless liquid is one of the four isomeric amines of butane, the others being sec-butylamine, tert-butylamine and isobutylamine. At standard temperature and pressure, n-butylamine is a liquid having the fishy, ammonia-like odor common to amines. The liquid acquires a yellow color upon storage in air. It is soluble in all organic solvents.

Like other simple, aliphatic amines, n-butylamine is a weak base, with a pKa, in its protonated form, of 10.59.[2]


This compound is used as an ingredient in the manufacture of pesticides (such as thiocarbazides), pharmaceuticals, and emulsifiers. It is also a precursor for the manufacture of N,N'-dibutylthiourea, a rubber vulcanization accelerator, and n-butylbenzenesulfonamide, a plasticizer of nylon.


The LD50 to rats through the oral exposure route is 366 mg/kg.[3]

In regards to occupational exposures to n-Butylamine, the Occupational Safety and Health Administration and National Institute for Occupational Safety and Health have set occupational exposure limits at a ceiling of 5 ppm (15 mg/m3) for dermal exposure.[4]


  1. ^ "n-butylamine - Compound Summary". PubChem Compound. USA: National Center for Biotechnology Information. 26 March 2005. Identification and Related Records. Retrieved 8 May 2012. 
  2. ^ H. K. Hall (1957) J. Am. Chem. Soc. 79 5441.
  3. ^ n-Butylamine MSDS
  4. ^ CDC - NIOSH Pocket Guide to Chemical Hazards