NDUFA10

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NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa
Identifiers
Symbols NDUFA10 ; CI-42KD; CI-42k
External IDs OMIM603835 MGI1914523 HomoloGene15342 ChEMBL: 2089 GeneCards: NDUFA10 Gene
EC number 1.6.5.3, 1.6.99.3
RNA expression pattern
PBB GE NDUFA10 217860 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 4705 67273
Ensembl ENSG00000130414 ENSMUSG00000026260
UniProt O95299 Q99LC3
RefSeq (mRNA) NM_004544 NM_024197
RefSeq (protein) NP_004535 NP_077159
Location (UCSC) Chr 2:
240.83 – 240.96 Mb
Chr 1:
92.44 – 92.47 Mb
PubMed search [1] [2]

NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial is an enzyme that in humans is encoded by the NDUFA10 gene.[1][2]

The protein encoded by this gene belongs to the complex I 42kDA subunit family. Mammalian complex I is the first enzyme complex in the electron transport chain of mitochondria. It is composed of 45 different subunits. This protein is a component of the hydrophobic protein fraction and has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain.[2]

References[edit]

  1. ^ Loeffen JL, Triepels RH, van den Heuvel LP, Schuelke M, Buskens CA, Smeets RJ, Trijbels JM, Smeitink JA (Jan 1999). "cDNA of eight nuclear encoded subunits of NADH:ubiquinone oxidoreductase: human complex I cDNA characterization completed". Biochem Biophys Res Commun 253 (2): 415–22. doi:10.1006/bbrc.1998.9786. PMID 9878551. 
  2. ^ a b "Entrez Gene: NDUFA10 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa". 

Further reading[edit]