NDUFV3

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NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa
Identifiers
Symbols NDUFV3 ; CI-10k; CI-9KD
External IDs OMIM602184 MGI1925580 HomoloGene10885 GeneCards: NDUFV3 Gene
EC number 1.6.5.3
Orthologs
Species Human Mouse
Entrez 4731 78330
Ensembl ENSG00000160194 ENSMUSG00000024038
UniProt P56181 Q8BK30
RefSeq (mRNA) NM_001001503 NM_001083891
RefSeq (protein) NP_001001503 NP_001077360
Location (UCSC) Chr 21:
44.3 – 44.33 Mb
Chr 17:
31.52 – 31.53 Mb
PubMed search [1] [2]

NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial is an enzyme that in humans is encoded by the NDUFV3 gene.[1][2]

The protein encoded by this gene is one of at least forty-one subunits that make up the NADH-ubiquinone oxidoreductase complex. This complex is part of the mitochondrial respiratory chain and serves to catalyze the rotenone-sensitive oxidation of NADH and the reduction of ubiquinone. The encoded protein is one of three proteins found in the flavoprotein fraction of the complex. The specific function of the encoded protein is unknown. Two transcript variants encoding different isoforms have been found for this gene.[2]

References[edit]

  1. ^ de Coo RF, Buddiger P, Smeets HJ, van Oost BA (Feb 1998). "Molecular cloning and characterization of the human mitochondrial NADH:oxidoreductase 10-kDa gene (NDUFV3)". Genomics 45 (2): 434–7. doi:10.1006/geno.1997.4930. PMID 9344673. 
  2. ^ a b "Entrez Gene: NDUFV3 NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa". 

Further reading[edit]