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Nescient helix loop helix 1
Symbols NHLH1 ; HEN1; NSCL; NSCL1; bHLHa35
External IDs OMIM162360 MGI98481 HomoloGene4089 GeneCards: NHLH1 Gene
RNA expression pattern
PBB GE NHLH1 214628 at tn.png
More reference expression data
Species Human Mouse
Entrez 4807 18071
Ensembl ENSG00000171786 ENSMUSG00000051251
UniProt Q02575 Q02576
RefSeq (mRNA) NM_005598 NM_010916
RefSeq (protein) NP_005589 NP_035046
Location (UCSC) Chr 1:
160.34 – 160.34 Mb
Chr 1:
172.05 – 172.06 Mb
PubMed search [1] [2]

Helix-loop-helix protein 1 is a protein that in humans is encoded by the NHLH1 gene.[1]

The helix-loop-helix (HLH) proteins are a family of putative transcription factors, some of which have been shown to play an important role in growth and development of a wide variety of tissues and species. Four members of this family have been clearly implicated in tumorigenesis via their involvement in chromosomal translocations in lymphoid tumors: MYC (MIM 190080), LYL1 (MIM 151440), E2A (MIM 147141), and SCL (MIM 187040).[supplied by OMIM][1]


Further reading[edit]