NHLH1

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Nescient helix loop helix 1
Identifiers
Symbols NHLH1 ; HEN1; NSCL; NSCL1; bHLHa35
External IDs OMIM162360 MGI98481 HomoloGene4089 GeneCards: NHLH1 Gene
RNA expression pattern
PBB GE NHLH1 214628 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 4807 18071
Ensembl ENSG00000171786 ENSMUSG00000051251
UniProt Q02575 Q02576
RefSeq (mRNA) NM_005598 NM_010916
RefSeq (protein) NP_005589 NP_035046
Location (UCSC) Chr 1:
160.34 – 160.34 Mb
Chr 1:
172.05 – 172.06 Mb
PubMed search [1] [2]

Helix-loop-helix protein 1 is a protein that in humans is encoded by the NHLH1 gene.[1]

The helix-loop-helix (HLH) proteins are a family of putative transcription factors, some of which have been shown to play an important role in growth and development of a wide variety of tissues and species. Four members of this family have been clearly implicated in tumorigenesis via their involvement in chromosomal translocations in lymphoid tumors: MYC (MIM 190080), LYL1 (MIM 151440), E2A (MIM 147141), and SCL (MIM 187040).[supplied by OMIM][1]

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