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NLR family, pyrin domain containing 9
Symbols NLRP9 ; CLR19.1; NALP9; NOD6; PAN12
External IDs OMIM609663 MGI2675377 HomoloGene18530 IUPHAR: 1776 GeneCards: NLRP9 Gene
Species Human Mouse
Entrez 338321 243874
Ensembl ENSG00000185792 ENSMUSG00000060508
UniProt Q7RTR0 Q66X22
RefSeq (mRNA) NM_176820 NM_194058
RefSeq (protein) NP_789790 NP_918947
Location (UCSC) Chr 19:
56.22 – 56.25 Mb
Chr 7:
20.01 – 20.07 Mb
PubMed search [1] [2]

NLRP9, short for NOD-like receptor family pyrin domain containing 9, is an intracellular protein that is expressed in the ovaries, testes, oocytes, and preimplantation embryos of mammals that is likely involved in reproductive processes.[1][2][3] It is also known as NALP9, NOD6, PAN12, and CLR19.1, and is one of 14 pyrin domain containing members of the NOD-like receptor family of cytoplasmic receptors.


  1. ^ Dalbiès-Tran R, Papillier P, Pennetier S, Uzbekova S, Monget P (August 2005). "Bovine mater-like NALP9 is an oocyte marker gene". Mol. Reprod. Dev. 71 (4): 414–21. doi:10.1002/mrd.20298. PMID 15892040. 
  2. ^ Ponsuksili S, Brunner RM, Goldammer T et al. (March 2006). "Bovine NALP5, NALP8, and NALP9 genes: assignment to a QTL region and the expression in adult tissues, oocytes, and preimplantation embryos". Biol. Reprod. 74 (3): 577–84. doi:10.1095/biolreprod.105.045096. PMID 16339045. 
  3. ^ Tian X, Pascal G, Monget P (2009). "Evolution and functional divergence of NLRP genes in mammalian reproductive systems". BMC Evol. Biol. 9: 202. doi:10.1186/1471-2148-9-202. PMC 2735741. PMID 19682372. 

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