NUP205

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Nucleoporin 205kDa
Identifiers
Symbols NUP205 ; C7orf14
External IDs OMIM614352 MGI2141625 HomoloGene45971 GeneCards: NUP205 Gene
Orthologs
Species Human Mouse
Entrez 23165 70699
Ensembl ENSG00000155561 ENSMUSG00000038759
UniProt Q92621 E9Q880
RefSeq (mRNA) NM_015135 NM_027513
RefSeq (protein) NP_055950 NP_081789
Location (UCSC) Chr 7:
135.24 – 135.33 Mb
Chr 6:
35.18 – 35.25 Mb
PubMed search [1] [2]

Nuclear pore complex protein Nup205 also known as nucleoporin 205kDa is a protein that in humans is encoded by the NUP205 gene.[1][2][3]

Function[edit]

Transport of macromolecules between the cytoplasm and nucleus occurs through nuclear pore complexes (NPCs) embedded in the nuclear envelope. NPC's are composed of subcomplexes, and NUP205 is part of one such subcomplex.[1]

References[edit]

  1. ^ a b "Entrez Gene: NUP205 nucleoporin 205kDa". 
  2. ^ Nagase T, Seki N, Ishikawa K, Ohira M, Kawarabayasi Y, Ohara O, Tanaka A, Kotani H, Miyajima N, Nomura N (October 1996). "Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain". DNA Res. 3 (5): 321–9, 341–54. doi:10.1093/dnares/3.5.321. PMID 9039502. 
  3. ^ Grandi P, Dang T, Pané N, Shevchenko A, Mann M, Forbes D, Hurt E (October 1997). "Nup93, a Vertebrate Homologue of Yeast Nic96p, Forms a Complex with a Novel 205-kDa Protein and Is Required for Correct Nuclear Pore Assembly". Mol. Biol. Cell 8 (10): 2017–38. doi:10.1091/mbc.8.10.2017. PMC 25664. PMID 9348540. 

Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.