Nucleoporin 54

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Nucleoporin 54kDa
Symbols NUP54 ; MGC13407
External IDs OMIM607607 MGI1920460 HomoloGene41169 GeneCards: NUP54 Gene
RNA expression pattern
PBB GE NUP54 218256 s at tn.png
More reference expression data
Species Human Mouse
Entrez 53371 269113
Ensembl ENSG00000138750 ENSMUSG00000034826
UniProt Q7Z3B4 Q8BTS4
RefSeq (mRNA) NM_001278603 NM_183392
RefSeq (protein) NP_001265532 NP_899248
Location (UCSC) Chr 4:
77.04 – 77.07 Mb
Chr 5:
92.42 – 92.44 Mb
PubMed search [1] [2]

Nucleoporin 54 (Nup54) is a protein that in humans is encoded by the NUP54 gene.[1][2]


The nuclear envelope creates distinct nuclear and cytoplasmic compartments in eukaryotic cells. It consists of two concentric membranes perforated by nuclear pores, large protein complexes that form aqueous channels to regulate the flow of macromolecules between the nucleus and the cytoplasm. These complexes are composed of at least 100 different polypeptide subunits, many of which belong to the nucleoporin family. This gene encodes a member of the phe-gly (FG) repeat-containing nucleoporin subset.[2]


Further reading[edit]