Sirota is best known for her singular sound and expressive execution, coaxing solo works from the likes of Nico Muhly, Daníel Bjarnason, Judd Greenstein, Marcos Balter and Missy Mazzoli.[b] Her debut album First Things First was released in 2009 on New Amsterdam Records and cited as a record of the year by The New York Times, and her second album, Baroque, was released in March 2013. In 2012, she recorded Nico Muhly's "Drones & Piano" with pianist Bruce Brubaker; it appears on the Bedroom Community recording Drones.
In addition to her work as a soloist, Sirota is a member of yMusic, ACME (the American Contemporary Music Ensemble) and Alarm Will Sound, and has lent her sound to recording and concert projects by such artists and songwriters as Grizzly Bear, Jónsi and Arcade Fire. Sirota also hosts a radio show on WQXR's New Music radio stream, Q2Music, for which she was awarded the 2010 ASCAP Deems Taylor Award in Radio and Internet Broadcasting. Sirota is the recipient of Southern Methodist University's 2013 Meadows Prize, awarded to pioneering artists and scholars with an emerging international profile. She received her undergraduate and Masters degrees from the Juilliard School, and since 2007 has been on faculty at the Manhattan School of Music in their Contemporary Performance Program. 
|2009||First Things First||with Judd Greenstein and Clarice Jensen|
|2014||In the Hollows||Dead Heart Bloom|
|2013||Secrets of Antikythera||Meredith Monk|
|2013||Trouble Will Find Me||The National|
|2013||Traveling Alone||Tift Merritt|
|2012||Swing Lo Magellan||Doveman|
|2012||Sugaring Season||Beth Orton|
|2012||Architecture of Loss||Valgeir Sigurðsson|
|2011||Lar Fleur de L'Aube||Arcade Fire|
|2011||Songs of Ascension||Nico Muhly|
|2011||Puzzle Muteson||En Garde|
|2011||All Things Will Unwind||My Brightest Diamond|
|2010||The Suburbs||Nat Baldwin|
|2010||Strange Waves||Dirty Projectors|
|2010||I Drink the Air Before Me||Nico Muhly|
|2010||High Violet||The National|
|2010||Strange Weather, Isn't It?||!!!|
|2009||The Conformist||Faux Fix|
|2008||A Thousand Shark's Teeth||My Brightest Diamond|
|2006||Speaks Volumes||Nico Muhly|
-  "The viola is one of those soulful, lost-in-the- middle instalments that occasionally erupt into the foreground — when Nadia Sirota is handling one, for example."
-  "Muhly formed alliances with a number of musicians who have become regular collaborators, including Nadia Sirota, a violist. Sirota says of Muhly, "He is different from a lot of composers his age in that he prefers a kind of old-school way."
- New York - Volume 42 Nos 15-22 2009
- The New Yorker - Volume 84, Nos 1-7 - Page 81 2008
- Kozinn, Allan (Holiday 2009). "Classical Music Gift Guide”". The New York Times.
- . ASCAP http://www.ascap.com/press/2010/1108_taylorawards.aspx. Retrieved 10 May 2014. Missing or empty
- . Manhattan School of Music http://www.msmnyc.edu/FacultyBio/fid/1019017303. Retrieved 10 May 2014. Missing or empty