Nalorphine

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Nalorphine
Nalorphine.svg
Systematic (IUPAC) name
(5α,6α)-17-allyl- 7,8-didehydro- 4,5-epoxymorphinan- 3,6-diol
Clinical data
AHFS/Drugs.com International Drug Names
Legal status Prescription Only (S4) (AU)
Identifiers
CAS number 62-67-9 YesY
ATC code V03AB02
PubChem CID 5284595
IUPHAR ligand 1629
ChemSpider 4447643 YesY
UNII U59WB2WRY2 N
ChEMBL CHEMBL415284 N
Synonyms (−)−(5R,6S)-9α-allyl- 4,5-epoxymorphin- 7-en- 3,6-diol
Chemical data
Formula C19H21NO3 
Mol. mass 311.375 g/mol
 N (what is this?)  (verify)

Nalorphine (INN; Lethidrone, Nalline), also known as N-allyl-normorphine, is a mixed opioid agonist-antagonist. It acts at two opioid receptors, at the mu receptor it has antagonistic effects and at the kappa receptors it exerts high-efficacy agonistic characteristics. It is used to reverse opioid overdose and (starting in the 1950s) in a challenge test to determine opioid dependence.[1]

See also[edit]

References[edit]

  1. ^ "Medicine: Drug Detector", Time, Dec. 24, 1956