The train is named after one of the seven hills of Tirupathi. The train departs from Secunderabad at 18:05 hours and arrives in Tirupati Railway Station at 06:05 hours the next day. From Tirupati Railway Station, the train departs at 18:25 hours and arrives in Secunderabad at 06:25 hours the next day.
The train usually has a 1AC and 2AC combo coach(added in Sep'09), 1 AC 2-Tier Coach, 2 AC 3-Tier Coaches, 14 Sleeper Class Coaches, 1 Pantry Car, and 3 General Compartments and 2SLR's. A rake of the Narayanadri Express consists of 24 Coaches. It shares its rakes with the Falaknuma Express. One can see the Tirupati-Secunderabad-Howrah boards in the rakes.