Folsom was born into a large family in Exeter, New Hampshire. His ancestors were among Exeter's earliest settlers, having arrived with the Gilman family, to whom they were related, from Hingham, Massachusetts, where both families settled for a time before moving on to New Hampshire. (The original spelling of the family name was Foulsham. The Folsoms continued to hold land outside Hingham, Norfolk, England, many years after leaving for the Massachusetts Bay Colony. In 1673, John Folsom of Exeter gave his son Peter 50 acres (200,000 m2) of land in Norfolk County, England, which he had inherited from his family.) Nathaniel Folsom's father, Jonathan (c. 1685–1740) married Ann Ladd (1691–1742), and she gave birth to Anna, Sarah, Lydia, Elizabeth, Abigail, John, Mary, Nathaniel, Jonathan, Samuel, Josiah and Trueworthy (named for Folsom's Treworgy ancestors).
When Folsom's father died, in January 1740, the thirteen-year-old went to work for a merchant. He invested in timber and opened a saw-mill. Then in 1761, he went into business with some distant cousins, Joseph and Josiah Gilman. They became Folsom, Gilman & Gilman and opened a general store, built ships, and carried on an import/export business. The firm operated in Exeter and Portsmouth. Though the partners went their separate ways in 1768, Folsom continued in foreign commerce, timber, and lumber operations for the rest of his life.
Folsom married twice, first to Dorothy Smith (1726–1776). Their children included: Nathaniel, Dorothy, Jonathan, Anna, Arthur, and Mary (1751–1812), and Deborah; (Deborah was New Hampshire Governor John Taylor Gilman's first wife, Mary his second). By his second wife, Mary Sprague, he had one daughter, Ruth Weare Folsom.
Folsom joined the militia as did most young men. During the French and Indian War he was Captain of a company in the New Hampshire Provincial Regiment during the Crown Point expedition led by Sir William Johnson in 1755. At the Battle of Lake George, his company, supported by artillery from Massachusetts surprised and captured Baron Dieskau, the French commander-in-chief. Besides capturing the Baron, they dispersed the French troops, took the French baggage train and seized a critical mass of supplies, with the loss of only six men.
Folsom went on to become a colonel in the militia. His formal commission was revoked by Governor Wentworth after the raid on Fort William and Mary in December 1774. Disregarding this, Colonel Folsom marched his regiment to Portsmouth, and escorted the captured cannons safely back to Durham.
On May 29, 1775, the Provincial Congress named him a Brigadier General in command of New Hampshire's forces. This created some confusion, as the Massachusetts provisional government had named John Stark to the same position. At the time, Colonel Stark was the senior commander of the New Hampshire men who had marched to the Siege of Boston. The confusion was resolved in June, when the Continental Congress named John Sullivan General of those New Hampshire forces in service with the Continental Army. Folsom was the senior officer for militia forces within the state. He was later named a Major General, and continued recruiting, training, and supply efforts throughout the war.
Folsom had served several years as moderator of the town meetings at Exeter. When a revolutionary Assembly, the Provincial Congress, first met on July 21, 1774, he was a delegate. The Provincial Congress, in turn named him their delegate to the first Continental Congress that met in Philadelphia, Pennsylvania.
In 1775, Folsom continued his service in the provincial congress, as he would do until 1783. He became a close political ally of Meshech Weare and Josiah Bartlett, as he was named to the New Hampshire Committee of Safety. In January 1776, he also became a justice in the Rockingham County court of common pleas. In 1777 and 1779 he was also returned to his old post as a delegate to the Continental Congress.
In 1783 he became the chief judge in the common pleas court. That same year he went to, and presided over, the state's constitutional convention. When a constitution was adopted, as president of the convention, he wrote a cover letter, then forwarded it to the towns for ratification. Ironically, one problem addressed by the constitution was to limit the number of offices held by one man. Folsom resigned from the Assembly, and as head of the militia, and from the Governor's Council.
He held the job of chief judge in Rockingham County until his death in Exeter on May 26, 1790. He is buried in Exeter's Winter Street Cemetery.
- Gen. Nathaniel Folsom of Exeter, A Genealogy of the Folsom Family: John Folsom and His Descendants, 1615-1882, Jacob Chapman, The Republican Press Association, Concord, N.H., 1882
- Folsom's Congressional biography
- State Builders: An Illustrated Historical and Biographical Record of the State of New Hampshire. State Builders Publishing Manchester, NH 1903